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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

其中,在
大卫评价说:“这唱的太棒了,无可挑剔,简直完美。”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“Welcome to Me” (Shira Piven)
然后,事情峰回路转。库迪斯和沃斯发现,荷兰贷款机构对于Seppenwolde的倒闭做出的反应截然不同。那些曾经贷款给Seppenwolde、但一毛钱也没损失的贷款机构变得越发悲观,要求所有新借款人都提供更多的“折幅”。而那些从未贷款给Seppenwolde、因而躲过一劫的贷款机构则根本没有提高要求。事实上,这些贷款机构可能还略略降低了对借款人的“折幅”要求,至少表明他们和过去一样乐观。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

第三,麦克德莫特可以作为一道保险,以防如果今年夏天安德烈-罗伯森选择自由离开时雷霆无人可用。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

冲击奖项:如果这届奥斯卡最佳影片的提名数有9或10部电影的话,那么《逃出绝命镇》能占一个。乔登皮尔的剧本应该一定会被提名。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

[p?'lu:n]
他补充说道:“我很兴奋能有机会重返中国,并享受这个国家的文化以及把NBA现场比赛的激动直接带给中国球迷。”
的确,价格不是一切。但即使是看空者也同意:一切都有价格。
Ninety percent of the students believe their universities' guidance on entrepreneurship would help their future businesses. In addition, they professed appreciation for policies intended to encourage entrepreneurship.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

出演《美国队长3:英雄决裂》的斯嘉丽-约翰逊排名第三,收入为2500万美元,比去年下降了近30%。
祝你享尽新年佳节的快乐和新年的礼品。
的确,这种兴奋会导致上述团体的成员做出不切实际的声明。一些比特币开发者和投资者宣称,五年内,各大银行将接受比特币。比特币钱包Blockchain公司首席运营官彼得o史密斯承认,上述说法有些夸张。史密斯表示:“我听到很多预测称,很快全世界都将使用比特币,这些预测大都不现实。我们正试图做的,是一个相当大胆的生态系统,所以这将需要很长的时间。”
本文为与《创业者》杂志的合作内容。下文最初发表于Entrepreneur.com。

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 区域协调发展释放更多经济潜力
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

3. “Bridge of Spies” Years ago, Steven Spielberg entered the ranks of Pantheon Directors, to borrow the most exalted category in Andrew Sarris’s taxonomic “The American Cinema” — and there he remains.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

talented

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The 2017 grads of Tsinghua University earn an average salary of 9,065 yuan per month, according to the survey released by xinchou.cn, an internet salary survey and report provider.
8. Greenland sharks live for a very long time

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

超过了9月份11.2%的上涨幅度。
但科学研究和技术服务领域企业的高管薪酬却下降了4.2%。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Look up "side-splitting humor" in the dictionary and you should probably come across the trailer for Girls Trip, which is the funniest movie of 2017, no contest.
单词outrage 联想记忆:

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

请尊重一下那些支持你的人以及节目主持人,能在访谈开始前把口香糖吐了吗?
喜剧类最佳男配角:路易?安德森(Louie Anderson),《小丑梦摇篮》(Baskets)
节目8 创意儿童节目《剪花花》,邓鸣贺 邓鸣璐、中国舞蹈家协会南方舞蹈学校
n. 意识,知觉,自觉,觉悟

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Premiered on Jan 29, the drama received 7 points out of 10 on the country's popular review website Douban.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

A total of 1,300 fugitives suspected of economic crimes, 347 of whom were corrupt officials, returned to China from abroad to face justice last year, according to the country's top discipline watchdog.
Economists say that both the residential and commercial markets in Hong Kong will be hurt by the same factors: slower growth in China, the depreciation of the renminbi, a crackdown on corruption on the mainland, and predictions that the US’s low interest-rate environment is due to end. However, government cooling measures introduced in 2012 to reduce speculative investment in Hong Kong property are an additional damper on the residential sector.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 门窗市场竞争形势或两极分化
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

但同比而言,厦门涨幅为43.9%,排在第二位,仅落后于安徽省会合肥,后者为47.6%。65个城市同比上涨,5个城市同比下跌,这表明虽然房价可能不会像以前一样迅速攀升,但上涨仍然具有普遍性而且较有韧性。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Data also showed that the average salary for the top 100 colleges on the rankings increased by 1,818 yuan over last year, up 22.8 percent.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Yes. The government hasn’t won a vertical merger case in decades. According to the Department of Justice’s own review guidelines, “vertical mergers” between content owners like Time Warner and distributors like AT&T are much less worrisome than horizontal ones. Meanwhile, the Fang companies — Facebook, Amazon, Netflix and Google — now dominate the digital entertainment landscape, which makes the government’s argument that the merger of two old-media firms would fundamentally alter competition even harder to make.
随着中国实力的抬升,其最好的友敌美国占了前10名的另一半。第5名和第9名分别是伯克希尔哈撒韦保险公司以及富国银行,这两家公司相较去年的排名均上升4位。
根据人社部、财政部近日联合下发的通知,企业和机关事业单位退休人员的月均养老金将在2016年的基础上上调约5.5%。
['debju]

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

12月8日,佳士得(Christie’s)的双年夜间拍卖会仅拍得650万英镑(含佣金),约合970万美元,而最低预估价为1270万英镑。45件作品中有19件流拍,比例达42%,包括两幅估价最高的作品——阿尔布雷特·丢勒(Albrecht Dürer)的学生汉斯·霍夫曼(Hans Hoffmann)1582年创作的水彩习作——丛林中的野兔,还有弗朗西斯科·瓜尔迪(Francesco Guardi)在18世纪70年代创作的描绘威尼斯圣乔治马焦雷岛美景的油画,这两幅画的最低估价分别是400万英镑和150万英镑。
creative
《沃兹汽车》将于1月15日在底特律一个与北美国际汽车展(North American International Auto Show)联合举办的仪式上颁发十大最佳引擎奖。
Best chances: Sally Hawkins is only a fraction behind current best actress favorite Frances McDormand.
“当前是经济动荡时期,但我们看到中国企业满怀信心地行动,继续在欧洲和北美做出大动作,”他说。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

vt. 补给,供
The group’s leader, Wang Rongzhen, told Reuters on Wednesday that the automaker has scaled back the range of models it supplies to dealers in Hyundai imports in China, only consistently supplying one model, while steadily increasing car manufacturing in China.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 北京朝阳将建十座地区文化中心
Critical Review

The role of biosensors in the detection of emerging infectious diseases

The 500 brands come from 28 different countries, among which nearly half, 227, are from the US.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

adj. 可能的,潜在的

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。
campaign
v
TAXES: Approximately $41,684 a year

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

2014年,世界杯在1978年以后又重新回到南美的怀抱,当时,马里奥·肯佩斯(Mario Kempes)带领阿根廷队战胜了荷兰队,保持着南美球队在南美洲大陆上举行的世界杯中赢得冠军的记录。那么,2014年会有所不同吗?包括卫冕冠军西班牙队在内的欧洲诸强能够实现那些在过去的比赛中的欧洲球队未能做到的吗?抑或,有其他任何大陆能够有实力挑战强大的南美球队吗?
bene好,fit做-做事后的好处
[slais]
The EU’s Americas gambits

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

n. 版权,著作权
美国公司高管的薪酬不断上升,收入差距越拉越大。在这种情况下,看到一位不光关心自身收入的CEO不禁让人眼前一亮。9月份,联想首席执行官杨元庆宣布,他将连续第二年和大约1万名联想员工分享他的奖金,数额至少为300万美元。他做出这个慷慨决定的原因是这家个人电脑制造商的年度销售额创下了历史新高。据彭博新闻(Bloomberg News)报道,参与“分成”的联想员工获得的奖金大约相当于中国普通城镇就业者一个月的收入。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

With Westbrook playing such a hands-on, high-usage role and Victor Oladipo already locked in on a high-dollar extension, Payne needed to prove he could be an off-ball threat or a lead guard on the second unit.
早先一个由活动分子和美国人权基金在一月份投放100000份电影的计划被推迟到了上个月的新年后。
联合国下属的国际农业发展基金会(IFAD)上周三表示,2016年,约有2亿名打工人员--其中一半是女性--向他们在亚洲、拉美和非洲的家人汇款4450亿美元。
但是我们波士士顿波士顿咨询集团不认为中国本次改革会导致中国经济不稳定。我们相信中国经济在习主席的领导下会持续高速增长。我们相信上个星期的改革(三中全会)会确保中国经济从现在一直增长到(至少)2020年。根据我们已掌握的资料,我们预测中国经济在未来10年会增加4万亿美金(而书中说是6.4万亿。2012中国GDP为8.3万亿美金)。如果加上印度,亚洲两大国未来的增长总量会达到10万亿美金。在此期间,中产阶级会迅速膨胀,进而增强对经济增长的乐观态度。当然,没有人能完美地预测未来,在我们的近期的一本关于中国和印度经济发展的书中(《Trillion Prize:Captivating the Newly Affluent in China and India》),我们也描述了一些经济增长缓慢的例子。不过总体上我们还是对中国的未来保持乐观态度。
Japanese Three: Honda treads water while it waits for bold new designs from its Americanized management team to reach market, particularly the Acura NSX super car, which has been on the auto show circuit now for several years. Focused now on his legacy, CEO Carlos Ghosn drives executives even harder to meet targets in his latest three-year plan while he grooms a successor. As for Toyota, Automotive News declares that it is firing on “all cylinders” before its move from Southern California with fresh products in key segments.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Social network Facebook Inc., e-commerce giant Amazon and toy company Lego were the top-growing brands.
“研究数据时,我不断回到这个问题上来,它其实是个身份政治问题,”挪威卑尔根大学(University of Bergen)研究欧洲极右翼党派的教授伊丽莎白?伊法斯夫拉腾(Elisabeth Ivarsflaten)说。“这是民粹主义者获得支持的最有力的征兆。”
来自的日本的Kazutaka Kurihara和 Koji Tsukada被授予声学奖,以奖励他们发明的“沉默枪”——这是一种可以打断人说话的机器,其原理是让说话者听到自己稍有延迟的说话声音,这个装置可以治疗在特定演讲中容易结巴的人。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

无论你相信与否,今年的搞笑文学奖被授予美国政府审计总署(GAO),以表彰他们发表的有关如何准备一份报告的报告的报告的报告……
Peace and love for you at New Year from all your students.祝老师新年充满平安和爱。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 市场:劣质防水卷材寿命不足一年
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

你一直感到压力很大
East New York in Brooklyn will be the test case when the Department of City Planning presents initial recommendations early next year. After that, the rezoning process could begin for the neighborhood, among the city’s poorest. A proposal for west Flushing in Queens is next.
n. 准学士学位获得

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

adj. 群众的,大规模
To ease women's concerns following the implementation of the two-child policy, the country should put in place more explicit regulations banning discrimination against women. These could include requiring companies to have a certain percentage of female employees, as well as tax cuts or other preferential measures to encourage employers to effectively implement the extended maternity leave regulation for female workers.
Many analysts may be surprised at the suggestion that they have underplayed the Fed. The two factors most often cited in relation to EM assets these days are the Fed and China, and the risk that they will deliver a negative shock.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

8)让我想想:是的,这话听起来有点像托词。有时,它就是托词。事实是,我们不可能任何时候都有权或有资格做决策。这句话为你赢得了思考的时间,你大可喘口气。然后,设定好日期及具体时间,做好跟进工作,让对方知道你很在乎他。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

从碧昂丝和珍妮弗·洛佩兹的红毯着装来看,“短”是这次娱乐盛典的主题。这两位女歌手都选择及大腿的裙子来露出她们的美腿,策略性地减去领口,并注重肩膀的细节设计,但碧昂丝选择穿消防车红色从中脱颖而出,而珍妮弗·洛佩兹选择了柔和的有缎子般光泽的褐土色。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

The youngest on the list is 19-year-old Norwegain heiress Alexandra Andresen, who holds a 42 per cent stake in her family's business. Her 20-year-old sister is the second youngest on the list.
"How many patients do Chinese doctors see a day? It can be more than 50," he told China Daily. "How can we have the time and energy to do research or publish papers?"

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

6.London's bike hire scheme couldn't be simpler, by the way: just go up to the terminal at any docking station, pay by card and take away one of our so-called "Boris bikes". When you're done with it, simply throw it into the nearest canal. They're disposable!
One of the things that makes Guardians such a great superhero franchise is its sense of humor—which is full of self-deprecation and sarcasm. It's not like you're going to watch this movie and laugh your way through it, but you'll at least have some moments of "ha ha, Groot," and "lolololol Chris Pratt."
The End of the Road
这名43岁的女子被判处为期12个月的行为考察,并且不得再次拥有宠物。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 加快陶瓷“制造”向“智造”转变
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Since April 2007, the value of the top 100 brands has increased by 106 per cent. That compares with a 61 per cent rise in the S&P 500 and growth of 21 per cent in the MSCI world index over the same period.
以人民币计算,12月份出口环比成功增长0.6%,超过了收缩0.1%的预期,不过仍大大低于11月份5.9%的增幅。以人民币计的进口增长10.8%,是预期4.8%的增幅的两倍以上,不过仍比上个月低2.2个百分点。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

adj. 突出的,显著的,未支付的
全食CEO约翰麦基的《自觉资本主义》(Conscious Capitalism)一书让公司高管们不得不思考这样一个观点,那就是处于最佳运转状态的企业能为所有利益相关方创造价值,而不仅仅是投资者。麦基认为,主要利益相关方包括顾客、员工、供应商、社会以及环境。他以好市多、西南航空(Southwest Airlines ,《财富》500强)和谷歌(Google,《财富》500强)为例,说明思维超越利润能够打造更强大而、更高效的公司。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

The potential impact of any surprise move in Fed policy was clear in the “taper tantrum” of 2013, when just the suggestion that the Fed might soon rein in its ultra-loose monetary policies was enough to provoke a wave of global panic.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

中国人民大学近日发布的我国大学生创业报告显示,学生学位与其创业意愿成反比。
In the MBA ranking, LBS, Insead and Spain’s IE Business School are bunched together with only a few dollars between them. Insead has the top salary at $155,015.
More than 70% said self-realization was the biggest motivation to start a business.
与去年相比,亚马逊(Amazon)、星巴克(Starbucks)和Facebook今年的品牌价值飙升。亚马逊的品牌价值增长59%,至990亿美元,排名第七,Elspeth Cheung表示,这在一定程度上源于其创造需求、而不仅仅是满足需求的能力。她表示,亚马逊的一小时送货服务对其他零售商加快送货速度构成压力,同时这家在线零售商进入物流领域对联合包裹(UPS)、联邦快递(FedEx)以及DHL等快递公司构成威胁。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

中国国家统计局(NBS)周四表示,最新房地产价格指数显示,11月新房价格同比下跌3.7%,为连续第三个月同比下跌,10月和9月分别同比下跌2.6%和1.3%。
和所有大学生一样,埃文o雷喜欢使用表情符号。但让他恼火的是,没有什么表情符号能够让他向圣母大学的同学表达自己对该校橄榄球队战斗的爱尔兰人的自豪感。于是,他和肖恩o欧布莱恩一起创办了一桩小生意,以弥补这一空白。这款名为TextPride的产品从体育和娱乐世界中获得图像授权,然后将其打包成贴纸出售。比如,在Kik这样的短信应用中,用户可以花1.99美元买一包迪斯尼电影《冰雪奇缘》的贴纸。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

IFAD的政策顾问、这篇报告的作者佩德罗·德·瓦斯孔塞卢斯称:“这确实是一个全球性的现象,由于缺乏机会,人们不得不背井离乡,出门打工养活家人。”
But there's little doubt this was also an 'acqui-hire,' in which the person being bought is just as important as the product. D'Aloisio is now working full time in Yahoo!'s London office, and his youth, his energy and his undeniable it-factor have brought the formerly musty tech giant a much-needed injection of cool. Yahoo! CEO Marissa Mayer -who lends the company some of her own it-factor-praises his 'commitment to excellence in design and simplicity' and says she is 'inspired by the creativity and tenacity Nick brings to his work.'
If 2017 was the year of fake news, 2018 is shaping up to be one of fake data. And just as fake news comes in many varieties — real news dubbed by the US president as fake, as well as nonsense gaining huge audiences on social media — so does fake data.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

1.哥吃的不是面,是寂寞。
可穿戴设备公司Atlas Wearables创始人彼得o李表示,电池技术和用户的保守是可穿戴市场面临的两大障碍。他说,在一些情况下,电池技术需要有足够大的改进才能实现足以激发用户兴趣的体验,而在穿戴时间、充电时间、处理能力和产品特点上,各家公司也需要做出平衡。
三大能源机构近期表示,今年石油输出国组织(Organization of the Petroleum Exporting Countries, 简称:欧佩克)以外国家的原油产量将增加,其中大部分来自美国的页岩油。除此之外,由于伊朗、伊拉克和利比亚可能会增产,中东地区的原油产量也许会增加数百万桶。所有这些势必会令油价承压。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 落实租售并举需加快建设REITs市场
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

3.2 深化重要领域和关键环节改革
Length of program: 21 months

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

《逃出绝命镇》
吉尔伯特称,冬季假期会让这个领域的热度降低,但真正的试金石在于各家公司能否开发出可以通过“返回考验”的可穿戴设备——如果人们已经走出了家门好几步,依然决定返回去取忘带了的可穿戴设备,就像他们去取忘掉的钱包、钥匙、手机一样,这个设备就成功了。
“即使你已经接受美联储加息的现实,也还有其他原因感到紧张,”美银美林(Bank of America Merrill Lynch)新兴市场负责人戴维樠纳(David Hauner)表示。他指出,油价不断下跌和中国经济增长放缓,是CBOE的VIX指数(反映投资者情绪的晴雨表)所衡量的市场波动水平自8月以来居高不下的其中两大原因。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

但是,当《老友记》第二季浓墨重彩地展现卡罗尔和苏珊的同性恋婚礼时,这个剧集就朝着人人平等的方向迈出了一大步。幕后,执行制片人玛塔·考夫曼说:"国家广播公司预计会接到成千上万的投诉电话和邮件"。然而在这部剧集上映之后,收到的恶意信件却是寥寥无几。原来,大家根本就不在乎。
Derrick Rose

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Several car names were among the top 50, from ‘ferrari’ to ‘mercedes.’
Ellen is a stand-up comedian and is best known for her self titled talk show, which she's hosted since 2003.
I'm only a child yet I know we are all part of a family, five billion strong, in fact, 30 million species strong and we all share the same air, water and soil -- borders and governments will never change that. 我只是一个小孩,但我知道我们都是一个大家庭的成员,超过60亿人的大家庭,以及超过三千万物种的大家庭,政府和国界永远都无法改变这个事实。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

3. 凯特?阿普顿

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
From the themed collection: 三棵树河南生产基地正式投产
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

reg统治,ulate-管制
汇丰发布的正式PMI指数从10月份的50.4降至11月份的50.0,这是6个月内的最低读数。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

We learned about fetal surgery’s potential to change lives.
Kate Winslet is another Brit who’s opted for the loo for her best actress Academy Award, which she was awarded for her complex role as a concentration camp guard in the 2008 adaptation of Bernhard Schlink’s novel, The Reader.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

[k?m'pein]
"The editors thought the articles were being sent out to genuine reviewers in the discipline," he said. "Following our investigation and communication with the real reviewers, they confirmed they did not conduct the peer review."

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Will José Antonio Meade be the next president of Mexico
Local champions

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

She has also performed on Jimmy Kimmel and The Ellen Show - not bad for someone who hasn't even hit adolescence.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

After enjoying a weekend of football in Manchester, David Beckham quickly jetted across the Pond to New York last night to spend Valentine’s Day with his p
单词bent 联想记忆:
凯文·史派西、摩根·弗里曼这样的明星也难逃一劫,被指控性侵演员,积极的网友在网上用标签分享各自的心路历程。
不过,日本央行(BoJ)仍决定不加大货币政策刺激力度。该行指出,工业产出是日本经济疲软的领域之一。当然,就业市场等日本经济的其他领域,表现要好得多。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
From the themed collection: 自住房满5年能转商品房吗?
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Strachan says that he believes that the IP-BOX uses the same method employed by the FBI to unlock the iPhone 5c used by Syed Farook, without Apple's help. The FBI is now offering to help other law enforcement agencies seeking to unlock an iPhone, iPad or Apple iPod touch. Apple is trying to discover how the FBI unlocked the phone so that it can issue a software update to close the vulnerability.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

单词pandemic 联想记忆:
联邦控制委员会要求修订的财政计划必须在1月底前批准,举出加西亚去年提交的部份是不现实的,并过度依赖联邦资金。加西亚拒绝提交一项修订计划,包括紧缩措施。罗塞略已经表示,他将要求延长还款期限与在2月到期的延缓偿付,目前保护波多黎各避免被愤怒的债权人诉讼。
Will Indian Prime Minister Narendra Modi try any more unorthodox economic experiments

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

如果我们问你“你想要多少月薪?”你应该说随便,或是根据工作责任而定。除非我们逼你,别自己说出一个具体的数。因为那只会让我们在商量上面占上风。
节目26 相声剧《搭把手不孤独》,冯巩 郭冬临 闫学晶

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

On the subject of #MeToo, she said: 'I just think they're douche bags. They're not champions. I just think they're losers. I don't like them.
神经系统科学家发现了小脑的一项全新功能。长期以来人们一直认为小脑基本上与意识直觉等活动无关,它的主要作用是协调站立、呼吸等基本的身体活动,然而,实际上小脑在影响人类行为上也发挥着重要作用。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 智能家居产品的创新之路在何方?
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Summly的两位员工将迁至雅虎的加利福尼亚州总部,但就目前而言,达洛伊西奥抵挡住了硅谷的诱惑。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Mr Karl added: “We would have likely had a record [year] even without El , but it pushed it way over the top.”
挪威两度拒绝成为欧盟成员国,整体排名为地第十。“公民权益”排名第一,“最透明”国度排名第二。
最后西蒙点评:“你们在唱的时候眼睛里透露出坚定,唱得相当投入,第一次我听到你们唱这首歌的时候我觉得很惊艳,而这一次提高了不少,更上了一个台阶。”

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

如果你已经为人父母,我能够理解,这是不太可能的。你会将孩子放在更重要的位置。但是,如果你没有在课堂上展示自己,那么你也就没有做到我们在第一点里讨论的内容。
Rents at the top end of the market have fallen 6.4 per cent, more sharply than in any other city except Nairobi, according to Knight Frank, the property company. Last year, just after prices fell in September, Adidas, the sportswear group, leased a 13,000 square foot shop in the city for 22 per cent less than its former occupier, Coach, the accessories brand.
Here, you may be delegates of your governments, business people, organisers, reporters or poiticians - but really you are mothers and fathers, brothers and sister, aunts and uncles - and all of you are somebody's child. 在这里,您可能是您政府商业人士的代表、组织者、记者或政客。但您们也是父亲和母亲、兄弟和姐妹、阿姨和叔叔,你们都会或多或少的为了下一代而活着。
? The transport infrastructure in New York City has been dealt a huge blow. Many of the city's subway tunnels are flooded.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

我知道你们中很多人在公司里曾经找到过自己的前任。但是,这不是放之四海皆准的规律。搞办公室恋情可能会对你产生不好的影响。
Floodwaters surround homes near the Mantoloking Bridge the morning after Sandy hit Mantoloking, New Jersey.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

据公安部介绍,2016年,1576名外国人成为中国永久性居民,较上一年度增长163%。
多年来,人们一直预测这个分散的行业将会整合,近期的确出现了大规模合并。但毫无疑问,伦敦金融城的律师事务所正在承受越来越大的价格压力。
Are you ready for a summer scare? Conjuring 2: The Enfield Poltergeist is set to hit the screens on June 10, 2016. We reckon that this is going to be a good horror movie.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 让“绿色”成为地板产业的推进剂
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About this collection

考克斯说:“没人真正知道末日是什么样子的,上帝又会如何让末日降临。”
樟宜机场集团总裁李绍贤先生表示:“连续五年获得Skytrax世界最佳机场的殊荣,这是对整个樟宜机场五万多名职员巨大的鼓励,我们每一位员工都极富热情,并且希望留给每一位旅客最难忘的候机经历。”

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